The Weird Reason Rabies Is So Deadly

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Rabies is the one of the deadliest diseases we know of; if you don’t get treatment soon after getting exposed, you’re almost certain to die. But rabies’ intent isn’t actually to kill – it's to control.

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To learn more about this topic, start your googling with these keywords:
- Neurotropic: infects nerve tissue
- Post-exposure prophylaxis (PEP): preventative medical treatment started after exposure to a pathogen

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Kate Yoshida | Script Writer, Narrator and Director
Arcadi Garcia i Rius | Storyboard Artist
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Nathaniel Schroeder | Music

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REFERENCES
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Bastos, V., Pacheco, V., Rodrigues, É. D., et al. (2023). Neuroimmunology of rabies: New insights into an ancient disease. Journal of Medical Virology, 95(10), e29042. doi.org/10.1002/jmv.29042

Brookes, V. J., Dürr, S., & Ward, M. P. (2019). Rabies-induced behavioural changes are key to rabies persistence in dog populations: Investigation using a network-based model. PLoS neglected tropical diseases, 13(9), e0007739. doi.org/10.1371/journal.pntd.0...

Fu, Z. F., & Jackson, A. A. C. (2005). Neuronal dysfunction and death in rabies virus infection. Journal of neurovirology, 11(1), 101-106. doi.org/10.1080/13550280590900...

Hueffer, K., Khatri, S., Rideout, et al. (2017). Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS. Scientific reports, 7(1), 12818. doi.org/10.1038/s41598-017-127...

Jackson, A. C. (2016). Diabolical effects of rabies encephalitis. Journal of neurovirology, 22(1), 8-13. doi.org/10.1007/s13365-015-035...

Lafon, M. (2011). Evasive strategies in rabies virus infection. In Advances in virus research (Vol. 79, pp. 33-53). Academic Press. doi.org/10.1016/b978-0-12-3870...
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